1,5-Bis(2-chlorophenyl)-1,4-pentadien-3-one → HCID 178479529, compound

HRID 441677Notes

Reaction equation

HRID 441677 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10](=O)[CH:11]=[CH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[Cl:19].Cl.[NH2:22][NH:23][C:24]([NH2:26])=[NH:25]>Cl.C(O)C>[ClH:1].[C:24]([NH:23][N:22]=[C:10]([CH:11]=[CH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[Cl:19])[CH:9]=[CH:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Cl:1])(=[NH:25])[NH2:26]

Participants

5

Reactant 2

HCID 2193691,5-Bis(2-chlorophenyl)-1,4-pentadien-3-oneHCID 178418668HCID 178418668, compound

Product 1

HCID 178479529HCID 178479529, compoundYield 124.6%

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidCatalystHCID 702EthanolSolvent

Procedure

Following the general procedure of Example 1, 9.1 grams of 1,5-bis(2-chlorophenyl)-1,4-pentadien-3-one, 4 grams of amino-guanidine hydrochloride, 10 drops of concentrated hydrochloric acid and 250 ml. of ethanol, and employing a 6.5 hour reflux period, 7.4 grams of the title compound is obtained, melting at 243°-244° C.

Workup

  1. temperaturereflux period

Sources & evidence

ORD record
ord-4262e88a22af4936bd7e3ecead441060
Source dataset
uspto-grants-1977_08
Patent number
USRE029358

Reaction notes

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