Ethanol → HCID 178430931, compound

HRID 441706Notes

Reaction equation

HRID 441706 reaction equation
O1[CH2:6][CH2:5][N:4]([C:7]2[C:12](=NO)[CH2:11][CH2:10][CH2:9][CH:8]=2)CC1.[CH2:15](O)C.[OH2:18].[NH2:19][NH2:20]>CC(C)=O>[CH3:6][C:5]1([CH3:15])[N+:4]([O-:18])=[C:7]2[CH2:12][CH2:11][CH2:10][CH2:9][C:8]2=[N:20][NH:19]1

Participants

5

Reactant 3

HCID 702EthanolHCID 24654Hydrazine hydrate (1:1)HCID 73454462HCID 73454462, compound

Product 1

HCID 178430931HCID 178430931, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

78.4 parts of 1-morpholino-6-oximino-cyclohex-1-ene in 400 parts of ethanol are heated with 20 parts of hydrazine hydrate for 2 hours under reflux and 46.4 parts of acetone are added. The reaction mixture is kept for 20 hours at 78° C. After cooling and filtering the mixture, 42 parts of 3,3-dimethyl-2,3,5,6,7,8,-hexahydro-1,2,4-benzo-triazine-4-oxide of melting point 119° C. (after recrystallization from acetone) are obtained; yield, 58% of theory.

Workup

  1. temperatureunder reflux
  2. temperatureAfter cooling
  3. filtrationfiltering
  4. customthe mixture, 42 parts of 3,3-dimethyl-2,3,5,6,7,8,-hexahydro-1,2,4-benzo-triazine-4-oxide of melting point 119° C. (after recrystallization from acetone)
  5. customare obtained
  6. customyield

Sources & evidence

ORD record
ord-5d4e10b5f32d428ca3e4f1d8f7f498e1
Source dataset
uspto-grants-1977_08
Patent number
US04042587

Reaction notes

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