反应详情

A mixture of 100 g of N-n-butyl-3,4-dichloroaniline (described in West German Pat. No. 1,902,419), 250 ml of isopropyl ether, 10 ml of triethylamine and 60 g of methyl isocyanate was stirred for 18 hours at room temperature and the solvent was distilled off under reduced pressure. The residue was added to petroleum ether (b.p.=65°-75° C.) and after cooling, the precipitate formed was recovered by vacuum filtration to obtain 59 g of N-methyl-N'-n-butyl-N'-(3,4-dichlorophenyl)-urea melting at 58° C.

1. distillationthe solvent was distilled off under reduced pressure
2. additionThe residue was added to petroleum ether (b.p.=65°-75° C.)
3. temperatureafter cooling
4. customthe precipitate formed
5. filtrationwas recovered by vacuum filtration