O-Xylene → 2-(3,4-Dimethylphenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol

HRID 442297Notes

Reaction equation

[F:1][C:2]([F:10])([F:9])[C:3]([C:5]([F:8])([F:7])[F:6])=[O:4].[CH3:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][C:17]=1[CH3:18]>>[OH:4][C:3]([C:14]1[CH:15]=[CH:16][C:17]([CH3:18])=[C:12]([CH3:11])[CH:13]=1)([C:5]([F:8])([F:7])[F:6])[C:2]([F:10])([F:9])[F:1]

Participants

Reactant 2

HCID 7237O-Xylene

HCID 12695Hexafluoroacetone

Product 1

HCID 144387072-(3,4-Dimethylphenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol

Procedure

This compound was prepared from o-xylene and hexafluoroacetone: bp 101°-102°/20.0 mm Hg; ND25 1.4334; lit. (1) bp 200-200.5°/760 mm Hg.

Sources & evidence

ORD record: ord-67114c8b2c2b4a66b1a4cad218332bfa
Source dataset: uspto-grants-1977_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04045408

Reaction notes

Loading…