Dimethylformamide → HCID 13668452, compound

HRID 442595Notes

Reaction equation

HRID 442595 reaction equation
[C:1]([O:11][C:12]1(C(O)=O)[CH:17]=[CH:16][C:15]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:14][CH2:13]1)(=[O:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].S(Cl)([Cl:29])=O.CN(C)[CH:33]=[O:34]>>[C:1]([O:11][C:12]1[CH:13]=[CH:14][C:15]([C:18]2[CH:19]=[CH:20][C:21]([C:33]([Cl:29])=[O:34])=[CH:22][CH:23]=2)=[CH:16][CH:17]=1)(=[O:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 67569445HCID 67569445, compound

Product 1

HCID 13668452HCID 13668452, compound

Procedure

4-n-Nonanoyloxybiphenyl-4-carboxylic acid (5.0 g) was added to thionyl chloride (10 g), and N,N-dimethylformamide in a very small amount was added to the mixture. The resulting mixture was refluxed for 4 hours. The unaltered thionyl chloride was removed by evaporation to give the desired compound (5.2 g).

Workup

  1. additionwas added to the mixture
  2. temperatureThe resulting mixture was refluxed for 4 hours
  3. customThe unaltered thionyl chloride was removed by evaporation

Sources & evidence

ORD record
ord-64c4e66e9622492aabc1407f28ea7793
Source dataset
uspto-grants-1999_04
Patent number
US05891359

Reaction notes

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