Sodium Hydroxide → HCID 69759324, compound

HRID 442655Notes

Reaction equation

HRID 442655 reaction equation
C([O:4][C:5]1[CH:28]=[CH:27][C:8](/[CH:9]=[C:10]2/[C:11](=[O:26])[NH:12]/[C:13](=[CH:17]\[C:18]3[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=3)/[C:14](=[O:16])[NH:15]/2)=[CH:7][CH:6]=1)(=O)C.[OH-].[Na+]>C1COCC1>[OH:4][C:5]1[CH:6]=[CH:7][C:8](/[CH:9]=[C:10]2/[C:11](=[O:26])[NH:12]/[C:13](=[CH:17]\[C:18]3[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=3)/[C:14](=[O:16])[NH:15]/2)=[CH:27][CH:28]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 69757387HCID 69757387, compound

Product 1

HCID 69759324HCID 69759324, compoundYield 30%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

(3Z,6Z)-3-(4-Acetoxybenzylidene)-6-(4-methoxybenzylidene)-2,5-piperazinedione was treated with aqueous sodium hydroxide in THF at room temperature for 8 hrs to give the title compound (1519) in 30% yield.

Sources & evidence

ORD record
ord-06afc42d4ffc4d90922b5f38c4453a6d
Source dataset
uspto-grants-1999_04
Patent number
US05891877

Reaction notes

Loading…