Hydrazine hydrate (1:1) → HCID 10638676, compound

HRID 442665Notes

Reaction equation

HRID 442665 reaction equation
[CH2:1]1[O:9][C:8]2[C:3](=[CH:4][C:5]([C:15](=O)[C:16]3[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=3)=[C:6]([CH2:10][C:11](OC)=[O:12])[CH:7]=2)[O:2]1.O.[NH2:26][NH2:27]>C(O)CC>[CH3:23][O:22][C:19]1[CH:20]=[CH:21][C:16]([C:15]2[C:5]3[CH:4]=[C:3]4[O:2][CH2:1][O:9][C:8]4=[CH:7][C:6]=3[CH2:10][C:11](=[O:12])[NH:27][N:26]=2)=[CH:17][CH:18]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 10735027Methyl 2-(4-Methoxybenzoyl)-4,5-methylenedioxyphenylacetate

Product 1

HCID 10638676HCID 10638676, compound

Reagents, catalysts & solvents 1

HCID 10311-PropanolSolvent

Procedure

The title compound was prepared from methyl 4,5-methylenedioxy-2-(4-methoxybenzoyl)phenylacetate (102 mg, 0.31 mmol) and hydrazine hydrate (30 μL, 0.53 mmol) in 1-propanol (8 mL), mp: 194°-196° C. 1H NMR (CDCl3) 8.48 (s, 1H), 7.55 (d, 2H, J=8.8), 6.94 (d, 2H, J=8.8), 6.83 (s, 1H), 6.66 (s, 1H), 6.03 (s, 2H), 3.86 (s, 3H), 3.44 (s, 2H). Anal. calcd. for C17H14N2O4 : C, 65.80; H, 4.55; N, 9.03. Found: C, 65.56; H, 4.57; N, 8.72.

Sources & evidence

ORD record
ord-794b1a448e4949ab9263aa5ecfe0e4a6
Source dataset
uspto-grants-1999_04
Patent number
US05891871

Reaction notes

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