Propionic Acid → HCID 13018767, compound

HRID 443458Notes

Reaction equation

HRID 443458 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([SH:8])=[CH:4][CH:3]=1.[NH2:9][CH2:10][CH2:11][CH2:12]O.[C:14]([OH:18])(=O)[CH2:15][CH3:16]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:12][CH2:11][CH2:10][NH:9][C:14](=[O:18])[CH2:15][CH3:16])=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 1032Propionic AcidHCID 7815p-ChlorothiophenolHCID 90863-Amino-1-propanol

Product 1

HCID 13018767HCID 13018767, compound

Procedure

The experiment of Example 1A was repeated in all essential details except that p-chlorobenzenethiol 50 g (0.67 mole), 3-aminopropanol 40.9 g (0.67 mole) and propionic acid 49.6 g (0.67 mole) were reacted. There was obtained N-[3(p-chlorophenylthio)propyl]propionamide, m.p. 69°-70° C. It was designated P-2135 for convenience. The nmr spectrum was consistent with the proposed structure. It analyzed as follows:

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-1c0a8c5f54b2401998fc41dcdafbc505
Source dataset
uspto-grants-1981_04
Patent number
US04260634

Reaction notes

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