Triphenylphosphine → HCID 20487382, compound

HRID 443626Notes

Reaction equation

HRID 443626 reaction equation
[Br:1][CH2:2][CH2:3][CH:4]([C:6]1[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=[C:8]([O:14][CH3:15])[CH:7]=1)[CH3:5].[C:16]1([P:22]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>C1(C)C(C)=CC=CC=1>[Br-:1].[CH3:15][O:14][C:8]1[CH:7]=[C:6]([CH:4]([CH3:5])[CH2:3][CH2:2][P+:22]([C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 12903417HCID 12903417, compound

Product 1

HCID 20487382HCID 20487382, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

The 3-(3,5-dimethoxyphenyl)butyltriphenylphosphonium bromide is prepared by refluxing a mixture of 1-bromo-3-(3,5-dimethoxyphenyl)butane (21.5 g., 78.5 mmoles) and triphenyl phosphine (20.5 g., 78.5 mmoles) in xylene (60 ml.) for 18 hours. The reaction mixture is then cooled to room temperature and filtered. The filter cake is washed with ether and dried in a vacuum desicator to give 36.4 g. (86%) yield of product; m.p. 190°-200° C.

Workup

  1. temperatureby refluxing
  2. filtrationfiltered
  3. washThe filter cake is washed with ether
  4. customdried in a vacuum desicator
  5. customto give 36.4 g

Sources & evidence

ORD record
ord-3cf1a73ad2244e499e15ce8625eb0dc2
Source dataset
uspto-grants-1981_04
Patent number
US04260764

Reaction notes

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