Tributylstannane → HCID 53849443, compound

HRID 443941Notes

Reaction equation

HRID 443941 reaction equation
[OH:1][C:2]1([CH3:19])[C:8]([CH3:10])(Br)[CH:7]([CH:11]=[CH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[O:6][C:4](=[O:5])[CH2:3]1.C([SnH](CCCC)CCCC)CCC>O1CCCC1>[OH:1][C:2]1([CH3:19])[CH:8]([CH3:10])[CH:7]([CH:11]=[CH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[O:6][C:4](=[O:5])[CH2:3]1

Participants

4

Reactant 2

HCID 5948TributylstannaneHCID 54438686HCID 54438686, compound

Product 1

HCID 53849443HCID 53849443, compoundYield 48.5%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The product obtained by reducing 680 mg of 3-hydroxy-3,4-dimethyl-4-bromo-7-phenyl-6-hepten-5-olide with 6.0 g of tri-n-butyltin hydride in 10 ml of anhydrous tetrahydrofuran according to the method described in Example 2 (a), was purified by a thin layer chromatography affording 250 mg of the desired compound as an oily substance.

Workup

  1. customThe product obtained
  2. customwas purified by a thin layer chromatography

Sources & evidence

ORD record
ord-bd3c41fb4ded438cb4d5b3eac94c7b77
Source dataset
uspto-grants-1981_04
Patent number
US04262013

Reaction notes

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