Salicylaldehyde → HCID 136195723, compound

HRID 444228Notes

Reaction equation

HRID 444228 reaction equation
[CH3:1][N:2]([C:4]1[S:8][N:7]=[C:6]([C:9]([Cl:12])([Cl:11])[Cl:10])[N:5]=1)[NH2:3].[CH:13](=O)[C:14]1[C:15](=[CH:17][CH:18]=[CH:19][CH:20]=1)[OH:16]>C(O)C>[CH3:1][N:2]([C:4]1[S:8][N:7]=[C:6]([C:9]([Cl:10])([Cl:12])[Cl:11])[N:5]=1)[N:3]=[CH:13][C:14]1[C:15](=[CH:17][CH:18]=[CH:19][CH:20]=1)[OH:16]

Participants

4

Reactant 2

HCID 6998SalicylaldehydeHCID 13014069HCID 13014069, compound

Product 1

HCID 136195723HCID 136195723, compoundYield 61%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
37 °C

Procedure

A mixture of 2.50 g (0.01 mole) 5-(1-methylhydrazino)-3-trichloromethyl-1,2,4-thiadiazole and 1.30 g (0.01 mole) salicylaldehyde was stirred. An exothermic reaction ensued and the reaction mixture warmed to 37° C. After 15 minutes ethanol was added and the solid product extracted. The product crystallized and was filtered to yield 2.15 g (61% yield) [mp. 207°-209° C. (dec)].

Workup

  1. customAn exothermic reaction
  2. extractionthe solid product extracted
  3. customThe product crystallized
  4. filtrationwas filtered
  5. customto yield 2.15 g (61% yield) [mp. 207°-209° C. (dec)]

Sources & evidence

ORD record
ord-83ca1c67b87b4701aa28be736926c8d0
Source dataset
uspto-grants-1981_04
Patent number
US04263312

Reaction notes

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