Triphenylphosphine → 3-(3-Methoxyphenyl)butyltriphenylphosphonium bromide

HRID 444362Notes

Reaction equation

HRID 444362 reaction equation
[Br:1][CH2:2][CH2:3][CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH3:13])[CH:7]=1)[CH3:5].[C:14]1([P:20]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C1(C)C(C)=CC=CC=1>[Br-:1].[CH3:13][O:12][C:8]1[CH:7]=[C:6]([CH:4]([CH3:5])[CH2:3][CH2:2][P+:20]([C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:11]=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 204969191-Bromo-3-(3-methoxyphenyl)butane

Product 1

HCID 204968783-(3-Methoxyphenyl)butyltriphenylphosphonium bromide

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

The 3-(3-methoxyphenyl)butyltriphenylphosphonium bromide is prepared by refluxing a mixture of 1-bromo-3-(3-methoxyphenyl)butane (78.5 mmoles) and triphenyl phosphine (78.5 mmoles) in xylene (60 ml.) for 18 hours. The reaction mixture is then cooled to room temperature and filtered. The filter cake is washed with ether and the product dried in a vacuum desiccator.

Workup

  1. temperatureby refluxing
  2. filtrationfiltered
  3. washThe filter cake is washed with ether
  4. customthe product dried in a vacuum desiccator

Sources & evidence

ORD record
ord-bd79032d7fc84ec7acd82b62acbf4d3b
Source dataset
uspto-grants-1981_04
Patent number
US04263438

Reaction notes

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