反应详情

温度

80 °C

A mixture of 6-bromo-2-isopropyl-4-nitro-1H-benzo[d]imidazole (4.7 g), 1-(bromomethyl)naphthalene (4.01 g) and K2CO3 (4.55 g) in DMF (150 mL) was stirred at 80° C. for 2 h. It was cooled to room temperature and filtered. The filtrate was then poured into water (1 L). It was then filtered to afford a solid that was washed with water and then dried in-vacuo to afford the crude product (7.2 g). LC-MS: m/e=425 [M+1]+

1. temperatureIt was cooled to room temperature
2. filtrationfiltered
3. additionThe filtrate was then poured into water (1 L)
4. filtrationIt was then filtered
5. customto afford a solid
6. washthat was washed with water
7. customdried in-vacuo