反应详情

Add a solution of hydrogen chloride in ether (1 M, 28 μL; 28.0 μmol) to a solution of 3-(6-hydroxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenoxy)naphthalen-2-yl)thiophene-2-carbonitrile (12 mg, 24.5 μmol) and dichloromethane (4 mL). Sonicate the mixture for 5 minutes and then concentrate to obtain the title compound (13 mg, 24.5 μmol). Mass spectrum (m/z): 471 (M+1-HCl).

1. customSonicate the mixture for 5 minutes
2. concentrationconcentrate