HRID446172

反应详情

EQUATION

反应方程式

HRID 446172 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

CONDITIONS

反应条件

温度
50 °C

PROCEDURE

实验过程

Phenyl isocyanate (3.6 ml, 32.6 mmol) was added to a solution of 4-[N-(1H-imidazol-1-yl)amino]benzonitrile (5 g, 27.17 mmol) in THF (50 ml). The mixture was stirred at 50° C. overnight and after evaporation was crystallised in acetone/EtOH to give white crystals (2.5 g, 30.3%, 178° C.).

WORKUP

后处理

  1. customafter evaporation
  2. customwas crystallised in acetone/EtOH
  3. customto give white crystals (2.5 g, 30.3%, 178° C.)