Allylamine → HCID 44481898, compound

HRID 452415Notes

Reaction equation

HRID 452415 reaction equation
Br[CH2:2][CH:3]1[O:8][C:7]2[CH:9]=[C:10]([S:13]([CH3:16])(=[O:15])=[O:14])[CH:11]=[CH:12][C:6]=2[CH2:5][O:4]1.[CH2:17]([NH2:20])[CH:18]=[CH2:19]>CCO>[CH3:16][S:13]([C:10]1[CH:11]=[CH:12][C:6]2[CH2:5][O:4][CH:3]([CH2:2][NH:20][CH2:17][CH:18]=[CH2:19])[O:8][C:7]=2[CH:9]=1)(=[O:15])=[O:14]

Participants

4

Reactant 2

HCID 7853AllylamineHCID 668864402-(bromomethyl)-7-(methylsulfonyl)-4H-1,3-benzodioxine

Product 1

HCID 44481898HCID 44481898, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Preparation according to Example 22 using 2-(bromomethyl)-7-(methylsulfonyl)-4H-1,3-benzodioxine (30 mg, 0.10 mmol), prop-2-en-1-amine (0.50 ml, 6.7 mmol) and EtOH (1.0 ml). MS m/z (rel. intensity, 70 eV) 283 (M+, 1), 123 (6), 77 (7), 71 (5), 70 (bp).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-d13403493b2647ce8b3e31c41008ad7f
Source dataset
uspto-grants-2013_07
Patent number
US08492372B2

Reaction notes

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