Hydrochloric Acid → HCID 58508967, compound

HRID 454561Notes

Reaction equation

HRID 454561 reaction equation
[OH-].[Na+].C([O:6][C:7]1[CH:31]=[C:30]([CH3:32])[CH:29]=[CH:28][C:8]=1[C:9]([NH:11][C:12]1[CH:21]=[C:20]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:19]=[CH:18][C:13]=1[C:14]([O:16]C)=[O:15])=[O:10])(=O)C.Cl>O1CCOCC1>[OH:6][C:7]1[CH:31]=[C:30]([CH3:32])[CH:29]=[CH:28][C:8]=1[C:9]([NH:11][C:12]1[CH:21]=[C:20]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:19]=[CH:18][C:13]=1[C:14]([OH:16])=[O:15])=[O:10]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 66990548HCID 66990548, compound

Product 1

HCID 58508967HCID 58508967, compoundYield 34.8%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Dioxane (3 mL) and a 2 mol/L aqueous solution of sodium hydroxide (1.7 mL) were added to the obtained methyl 2-(2-acetoxy-4-methylbenzamido)-4-phenylbenzoate (0.14 g), followed by stirring at room temperature for 2 hours and 30 minutes. The reaction mixture was adjusted to a pH of 3.0 with 6 mol/L hydrochloric acid. The solid substance was collected by filtration to obtain 0.042 g of 2-(2-hydroxy-4-methylbenzamido)-4-phenylbenzoic acid as a white solid.

Workup

  1. filtrationThe solid substance was collected by filtration

Sources & evidence

ORD record
ord-d1b8f75d4a544e0b8768fe5acd53051b
Source dataset
uspto-grants-2013_07
Patent number
US08492582B2

Reaction notes

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