反应详情

Thioanisole (1.6 mL) and trifluoroacetic acid (5.2 mL) were added to tert-butyl 2-(2-(benzyloxy)-5-(furan-3-yl)benzamido)-4-phenylbenzoate (0.14 g), followed by stirring at room temperature for 4 hours. The solvent was evaporated under reduced pressure, and dioxane was added to the residue. The solvent was evaporated under reduced pressure, and ethyl acetate was added to the residue. The solid substance was collected by filtration to obtain 0.020 g of 2-(5-(furan-3-yl)-2-hydroxybenzamido)-4-phenylbenzoic acid as a white solid.

1. customThe solvent was evaporated under reduced pressure, and dioxane
2. additionwas added to the residue
3. customThe solvent was evaporated under reduced pressure, and ethyl acetate
4. additionwas added to the residue
5. filtrationThe solid substance was collected by filtration