HRID454666

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6395

Methanesulfonic acid

CH4O3S

结构：CCN(CC)CCOc1ccc(O)c(C(=O)Nc2cc(-c3ccccc3)ccc2C(=O)O)c1

HCID58508815

未命名化合物

PRODUCTS

生成物

结构：CCN(CC)CCOc1ccc(O)c(C(=O)Nc2cc(-c3ccccc3)ccc2C(=O)O)c1.CS(=O)(=O)O

HCID86659241

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Ethanol (3.0 mL) and methanesulfonic acid (0.011 mL) were added to the obtained 2-(5-(2-(diethylamino)ethoxy)-2-hydroxybenzamido)-4-phenylbenzoic acid (0.079 g), followed by stirring at room temperature for 1 hour and 30 minutes. The solid substance was collected from the reaction mixture by filtration to obtain 0.049 g of 2-(5-(2-(diethylamino)ethoxy)-2-hydroxybenzamido)-4-phenylbenzoic acid methanesulfonate as a white solid.

WORKUP

后处理

filtrationThe solid substance was collected from the reaction mixture by filtration

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6570f6aa9a7a48549a2164cf95440d39
来源数据集: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08492582B2
来源说明: uspto-grants-2013_07

反应 SMILES

[CH3:1][S:2]([OH:5])(=[O:4])=[O:3].[CH2:6]([N:8]([CH2:37][CH3:38])[CH2:9][CH2:10][O:11][C:12]1[CH:13]=[CH:14][C:15]([OH:36])=[C:16]([CH:35]=1)[C:17]([NH:19][C:20]1[CH:28]=[C:27]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:26]=[CH:25][C:21]=1[C:22]([OH:24])=[O:23])=[O:18])[CH3:7]>C(O)C>[CH3:1][S:2]([OH:5])(=[O:4])=[O:3].[CH2:37]([N:8]([CH2:6][CH3:7])[CH2:9][CH2:10][O:11][C:12]1[CH:13]=[CH:14][C:15]([OH:36])=[C:16]([CH:35]=1)[C:17]([NH:19][C:20]1[CH:28]=[C:27]([C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)[CH:26]=[CH:25][C:21]=1[C:22]([OH:24])=[O:23])=[O:18])[CH3:38]