Methanesulfonic Acid → HCID 86659242, compound

HRID 454669Notes

Reaction equation

HRID 454669 reaction equation
[CH3:1][S:2]([OH:5])(=[O:4])=[O:3].[OH:6][C:7]1[CH:30]=[C:29]([O:31][CH2:32][CH2:33][N:34]2[CH2:39][CH2:38][O:37][CH2:36][CH2:35]2)[CH:28]=[CH:27][C:8]=1[C:9]([NH:11][C:12]1[CH:20]=[C:19]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:18]=[CH:17][C:13]=1[C:14]([OH:16])=[O:15])=[O:10]>C(O)C>[CH3:1][S:2]([OH:5])(=[O:4])=[O:3].[OH:6][C:7]1[CH:30]=[C:29]([O:31][CH2:32][CH2:33][N:34]2[CH2:39][CH2:38][O:37][CH2:36][CH2:35]2)[CH:28]=[CH:27][C:8]=1[C:9]([NH:11][C:12]1[CH:20]=[C:19]([C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:18]=[CH:17][C:13]=1[C:14]([OH:16])=[O:15])=[O:10]

Participants

4

Reactant 2

HCID 6395Methanesulfonic AcidHCID 58508522HCID 58508522, compound

Product 1

HCID 86659242HCID 86659242, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ethanol (2.0 mL) and methanesulfonic acid (0.010 mL) were added to the obtained 2-(2-hydroxy-4-(2-(morpholin-4-yl)ethoxy)benzamido)-4-phenylbenzoic acid (0.011 g), followed by stirring at room temperature for 3 hours and 30 minutes. The solvent was evaporated under reduced pressure, and ethanol was added to the obtained residue. The solid substance was collected by filtration to obtain 6.1 mg of 2-(2-hydroxy-4-(2-(morpholin-4-yl)ethoxy)benzamido)-4-phenylbenzoic acid methanesulfonate as a white solid.

Workup

  1. customThe solvent was evaporated under reduced pressure, and ethanol
  2. additionwas added to the obtained residue
  3. filtrationThe solid substance was collected by filtration

Sources & evidence

ORD record
ord-691c4fcaee684f04b4bbe0cc2f0fe0c1
Source dataset
uspto-grants-2013_07
Patent number
US08492582B2

Reaction notes

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