反应详情

The title compound was prepared according to the procedure described for compound 68 from methyl 1-((2-(4-chlorophenyl)imidazo[1,2-b]pyridazin-3-yl)methyl)-1H-imidazole-2-carboxylate and methylamine 1H-NMR (CDCl3, 400 MHz, δ) 8.54 (d, J=4.4 Hz, 1H), 8.09 (d, J=9.3 Hz, 1H), 7.87 (s, 1H), 7.64 (d, J=8.0 Hz, 2H), 7.51 (s, 1H), 7.47 (d, J=7.9 Hz, 2H), 7.37 (dd, J=4.5, 9.2 Hz, 1H), 6.93 (s, 1H), 6.90 (s, 1H), 6.31 (s, 2H), 2.91 (s, 3H) ppm; m/e 367 (M+H)+.