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HRID456764

反应详情

EQUATION

反应方程式

HRID 456764 的结构方程式

REACTANTS

反应物

3
结构：OCc1ccccc1
HCID244

Benzyl alcohol

C7H8O

结构：C(=NC1CCCCC1)=NC1CCCCC1
HCID10868

Dicyclohexylcarbodiimide

C13H22N2

结构：CC(C)(C)OC(=O)N1[C@@H]2C[C@@H](C[C@H]2O)[C@H]1C(=O)O
HCID69133789

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1[C@@H]2C[C@@H](C[C@H]2O)[C@H]1C(=O)OCc1ccccc1
HCID86598917

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CN(C)c1ccncc1
催化剂HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

To a solution of (1R,3S,4S,6R)-2-(tert-butoxycarbonyl)-6-hydroxy-2-azabicyclo[2.2.1]heptane-3-carboxylic acid obtained in Example 5-6 (1.0 g) in dichloromethane (8 mL), were added benzyl alcohol (504 mg), dicyclohexylcarbodiimide (962 mg) and 4-(dimethylamino)pyridine (12 mg). The mixture was stirred at room temperature for 20 hrs.