huagongshe.com
HRID458754

反应详情

EQUATION

反应方程式

HRID 458754 的结构方程式

REACTANTS

反应物

3
结构：O.O.O.O.O.O.O.O.O.O.O=S(=O)([O-])[O-].[Na+].[Na+]
HCID62649

Disodium sulfate decahydrate

H20Na2O14S

结构：CCOC(=O)CC1CCN(C(=O)OC(C)(C)C)CC1
HCID9993342

tert-Butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

C14H25NO4

结构：[Al+3].[H-].[H-].[H-].[H-].[Li+]
HCID21226445

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC(CCO)CC1
HCID854140

tert-Butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate

C12H23NO3

收率 93.1%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

To a solution of 263 mg of t-butyl 4-(2-ethoxy-2-oxoethyl)-tetrahydropyridine-1(2H)-carboxylate in 15 ml of tetrahydrofuran, 100 mg of lithiumaluminum hydride was added under cooling with ice, followed by 20 minutes' stirring at the same temperature. To the reaction liquid sodium sulfate decahydrate was added, stirred for 30 minutes and filtered with Celite. Distilling the solvent off under reduced pressure, 207 mg of the title compound was obtained.

WORKUP

后处理

  1. temperatureunder cooling with ice
  2. additionwas added
  3. stirringstirred for 30 minutes
  4. filtrationfiltered with Celite
  5. distillationDistilling the solvent off under reduced pressure