HRID458816

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID18066

1-Aminotetralin

C10H13N

HCID61147

Acetyl bromide, 2-bromo-

C2H2Br2O

结构：COc1ccc(CC2NCCSc3cc(OC)c(OC)cc32)cc1OC

HCID18442589

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(CC2c3cc(OC)c(OC)cc3SCCN2CC(=O)NC2CCCc3ccccc32)cc1OC

HCID18442579

未命名化合物

PROCEDURE

实验过程

prepared by reaction of 2-bromoacetyl bromide with rac-1,2,3,4-tetrahydro-naphthalen-1-ylamine and 9-(3,4-dimethoxy-benzyl)-2,3-dimethoxy-6,7,8,9-tetrahydro-5-thia-8-aza-benzocycloheptene.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9095804ee49942c3b274e248f01ed910
来源数据集: uspto-grants-2007_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07192950B2
来源说明: uspto-grants-2007_03

反应 SMILES

Br[CH2:2][C:3](Br)=[O:4].[CH:6]1([NH2:16])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9][CH2:8][CH2:7]1.[CH3:17][O:18][C:19]1[CH:20]=[C:21]([CH:38]=[CH:39][C:40]=1[O:41][CH3:42])[CH2:22][CH:23]1[C:29]2[CH:30]=[C:31]([O:36][CH3:37])[C:32]([O:34][CH3:35])=[CH:33][C:28]=2[S:27][CH2:26][CH2:25][NH:24]1>>[CH3:17][O:18][C:19]1[CH:20]=[C:21]([CH:38]=[CH:39][C:40]=1[O:41][CH3:42])[CH2:22][CH:23]1[C:29]2[CH:30]=[C:31]([O:36][CH3:37])[C:32]([O:34][CH3:35])=[CH:33][C:28]=2[S:27][CH2:26][CH2:25][N:24]1[CH2:2][C:3]([NH:16][CH:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9][CH2:8][CH2:7]1)=[O:4]