Oxalyl chloride → HCID 57083494, compound

HRID 458878Notes

Reaction equation

HRID 458878 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.C(Cl)(=O)C(Cl)=O.[O:18]=[C:19]1[C:28]2[C:23]3[C:24](=[CH:29][CH:30]=[CH:31][C:22]=3[C:21](=[O:32])[N:20]1[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][NH2:39])[CH:25]=[CH:26][CH:27]=2>>[O:18]=[C:19]1[C:28]2[C:23]3[C:24](=[CH:29][CH:30]=[CH:31][C:22]=3[C:21](=[O:32])[N:20]1[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][NH:39][C:9](=[O:11])[CH:8]=[CH:7][C:3]1[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=1)[CH:25]=[CH:26][CH:27]=2

Participants

4

Reactant 3

HCID 65578Oxalyl chlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 53758378HCID 53758378, compound

Product 1

HCID 57083494HCID 57083494, compound

Procedure

Batch size: 5.3 g (35.5 mmol) 3-(3-pyridyl)-acrylic acid, 12.4 g (97.9 mmol) oxalyl chloride and 8.6 g (32.6 mmol) 6-(1,3-dioxo-1H, 3H-benzo[de]isoquinolin-2-yl)-hexylamine.

Sources & evidence

ORD record
ord-9483434bcc1e4f8b989d4add147452c1
Source dataset
uspto-grants-2007_03
Patent number
US07192967B1

Reaction notes

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