Oxalyl chloride → HCID 68501739, compound

HRID 458879Notes

Reaction equation

HRID 458879 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.C(Cl)(=O)C(Cl)=O.[O:18]=[C:19]1[C:28]2[C:23]3[C:24](=[CH:29][CH:30]=[CH:31][C:22]=3[C:21](=[O:32])[N:20]1[CH2:33][CH2:34][NH2:35])[CH:25]=[CH:26][CH:27]=2>>[O:18]=[C:19]1[C:28]2[C:23]3[C:24](=[CH:29][CH:30]=[CH:31][C:22]=3[C:21](=[O:32])[N:20]1[CH2:33][CH2:34][NH:35][C:9](=[O:11])[CH:8]=[CH:7][C:3]1[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=1)[CH:25]=[CH:26][CH:27]=2

Participants

4

Reactant 3

HCID 65578Oxalyl chlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 110967192-(2-aMinoethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

Product 1

HCID 68501739HCID 68501739, compound

Procedure

Batch size: 7.5 g (50.4 mmol) 3-(3-pyridyl)-acrylic acid, 17.4 g (137.4 mmol) oxalyl chloride and 11.0 g (45.8 mmol) 2-(1,3-dioxo-1H, 3H-benzo[de]isoquinolin-2-yl)-ethylamine.

Sources & evidence

ORD record
ord-834887655ef842afa70a10b852b40d1d
Source dataset
uspto-grants-2007_03
Patent number
US07192967B1

Reaction notes

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