Ethyl Acetate → HCID 58822776, compound

HRID 459178Notes

Reaction equation

C(OC(=O)[CH:5]([C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][O:19][C:20]2[CH:25]=[CH:24][C:23]([O:26][C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)=[CH:22][C:21]=2[CH2:33][CH:34]=[CH2:35])=[CH:11][CH:10]=1)[CH2:6][O:7][CH3:8])C.[C:37]([O:40]CC)(=[O:39])C>>[CH3:8][O:7][C@@H:6]([CH2:5][C:9]1[CH:10]=[CH:11][C:12]([O:15][CH2:16][CH2:17][CH2:18][O:19][C:20]2[CH:25]=[CH:24][C:23]([O:26][C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)=[CH:22][C:21]=2[CH2:33][CH2:34][CH3:35])=[CH:13][CH:14]=1)[C:37]([OH:40])=[O:39]

Participants

Reactant 2

HCID 8857Ethyl Acetate

HCID 69425282HCID 69425282, compound

Product 1

HCID 58822776HCID 58822776, compound

Procedure

The title compound was prepared from 2-{4-[3-(2-Allyl-4-phenoxy-phenoxy)-propoxy]-phenyl}-3-methoxy-propionic acid ethyl ester from Example 160, Step B which was treated in ethyl acetate with Pd(C) and H2 in balloon presure to give after filtration the corresponding reduced product which was hydrolyzed under Standard Procedure C to give the title compound.

Workup

customto give
filtrationafter filtration the corresponding reduced product which

Sources & evidence

ORD record: ord-fe308e66e8b740179cf7de5d3c2ffcb5
Source dataset: uspto-grants-2007_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07192982B2

Reaction notes

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