反应详情

温度

25 °C

To a dichloromethane solution (10 ml/mmol) of tert-butyl 2-(2-(N-cyclopropyl-4-methoxy-2,6-dimethylphenylsulfonamido)ethoxy)acetate (1 equiv.) was added TFA (13 equiv.) at 0° C. and the resulting reaction mixture was stirred at 25° C. for 2 h. The solvent was evaporated off and the product dried under vacuum to remove traces of TFA. The crude acid was used directly for the next step without any further purification.

1. customthe resulting reaction mixture
2. customThe solvent was evaporated off
3. customthe product dried under vacuum
4. customto remove traces of TFA
5. customThe crude acid was used directly for the next step without any further purification