Sulfuric acid magnesium salt (1:1) → HCID 86593167, compound

HRID 459933Notes

Reaction equation

HRID 459933 reaction equation
Cl.[NH2:2][OH:3].C([O-])(=O)C.[Na+].S([O-])([O-])(=O)=O.[Mg+2].[F:15][C:16]([F:49])([F:48])[C:17]1[CH:18]=[C:19]([C@@H:27]([N:29]([CH3:47])[C:30]([N:32]2[CH2:37][CH2:36][C:35](=O)[CH2:34][C@@H:33]2[C:39]2[CH:44]=[CH:43][C:42]([F:45])=[CH:41][C:40]=2[CH3:46])=[O:31])[CH3:28])[CH:20]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:22]=1>CO>[F:49][C:16]([F:15])([F:48])[C:17]1[CH:18]=[C:19]([C@@H:27]([N:29]([CH3:47])[C:30]([N:32]2[CH2:37][CH2:36]/[C:35](=[N:2]/[OH:3])/[CH2:34][C@@H:33]2[C:39]2[CH:44]=[CH:43][C:42]([F:45])=[CH:41][C:40]=2[CH3:46])=[O:31])[CH3:28])[CH:20]=[C:21]([C:23]([F:26])([F:24])[F:25])[CH:22]=1

Participants

6

Reactant 4

HCID 24083Sulfuric acid magnesium salt (1:1)HCID 443297Hydroxyamine hydrochlorideHCID 517045Sodium AcetateHCID 57939525HCID 57939525, compound

Product 1

HCID 86593167HCID 86593167, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Hydroxylamine hydrochloride (695 mg), sodium acetate (820 mg) and dry magnesium sulphate (500 mg) were added to a solution of intermediate 5b (500 mg) in dry MeOH (50 mL) under a Nitrogen atmosphere.

Sources & evidence

ORD record
ord-fd8c3762c3294048955a5e6d1925b14a
Source dataset
uspto-grants-2007_03
Patent number
US07196077B2

Reaction notes

Loading…