Ethylamine → HCID 69497811, compound

HRID 460651Notes

Reaction equation

HRID 460651 reaction equation
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][CH:14]=[CH:13][C:4]=1[CH:5]=[C:6]1[C:10](=[O:11])O[C:8]([CH3:12])=[N:7]1.[CH2:17]([NH2:19])[CH3:18].C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH2:17]([N:19]1[C:10](=[O:11])[C:6](=[CH:5][C:4]2[CH:13]=[CH:14][CH:15]=[CH:16][C:3]=2[O:2][CH3:1])[N:7]=[C:8]1[CH3:12])[CH3:18]

Participants

5

Reactant 3

HCID 6341EthylamineHCID 11430Potassium CarbonateHCID 361416HCID 361416, compound

Product 1

HCID 69497811HCID 69497811, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
80 °C

Procedure

4-(2′-Methoxybenzylidene)-2-methyl-4H-oxazol-5-one (5 g) was dissolved in ethanol (100 ml) and an aqueous ethylamine solution (15 ml) and potassium carbonate (7 g) were added thereto. The mixture was heated at 80° C. for 5 hr. After cooling, the solvent was evaporated under reduced pressure and the precipitated yellow crystals were collected by filtration to give the title compound (1.2 g).

Workup

  1. temperatureAfter cooling
  2. customthe solvent was evaporated under reduced pressure
  3. filtrationthe precipitated yellow crystals were collected by filtration

Sources & evidence

ORD record
ord-426e205b5be049ff9d0fc599614c60e1
Source dataset
uspto-grants-2007_03
Patent number
US07196199B2

Reaction notes

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