Diazomethane → 4'-Methyl-3'-sulfamoyl-diazoacetophenone

HRID 461154Notes

Reaction equation

HRID 461154 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[S:11](=[O:14])(=[O:13])[NH2:12].[N+:15](=[CH2:17])=[N-:16]>C(OCC)C>[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](=[O:7])[CH:17]=[N+:15]=[N-:16])=[CH:4][C:3]=1[S:11](=[O:14])(=[O:13])[NH2:12]

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 227605604-Methyl-3-sulfamoyl-benzoyl chloride

Product 1

HCID 540475354'-Methyl-3'-sulfamoyl-diazoacetophenone

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

12 g of 4-methyl-3-sulfamoylbenzoyl chloride were reacted as prescribed in Example 66b) with diazomethane in diethyl ether and the substance precipitating as fair yellow precipitate was filtered off. Melting point: 176° C (decomposition).

Workup

  1. customthe substance precipitating as fair yellow precipitate
  2. filtrationwas filtered off

Sources & evidence

ORD record
ord-d01df7b968fc4bda8abbeb8f76885435
Source dataset
uspto-grants-1977_12
Patent number
US04061761

Reaction notes

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