Diisopropyl Ether → HCID 22760488, compound

HRID 461173Notes

Reaction equation

HRID 461173 reaction equation
C(NS([C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][C:17]=1[Cl:18])[C:12](Cl)=[O:13])(=O)=O)(C)(C)C.[N+](=[CH2:21])=[N-].C(NS(C1C=C(C(=O)C=[N+]=[N-])C=C[C:35]=1[Cl:36])(=O)=O)(C)(C)C.C(O[CH:46]([CH3:48])[CH3:47])(C)C>>[C:46]([C:9]1[CH:10]=[C:11]([C:12](=[O:13])[CH2:35][Cl:36])[CH:15]=[CH:16][C:17]=1[Cl:18])([CH3:48])([CH3:21])[CH3:47]

Participants

5

Reactant 4

HCID 7914Diisopropyl EtherHCID 9550DiazomethaneHCID 22760628HCID 22760628, compoundHCID 73997319HCID 73997319, compound

Product 1

HCID 22760488HCID 22760488, compound

Procedure

16 g of 3-tert.-butylsulfamoyl-4-chlorobenzoyl chloride were reacted as prescribed in Example 66b) with a solution of diazomethane in diisopropyl ether, sparingly soluble 3'-tert.-butylsulfamoyl-4'-chlorodiazoacetophenone being separated. The crystals were filtered and converted as prescribed in Example 66b) with concentrated HCl in diethyleneglycol dimethyl ether to yield 3'-tert.-butyl-2,4'-dichloroacetophenone. Colorless crystals, melting point: 159° C.

Workup

  1. customseparated
  2. filtrationThe crystals were filtered

Sources & evidence

ORD record
ord-0d2269cd0f6649fcb3330d2c7652da51
Source dataset
uspto-grants-1977_12
Patent number
US04061761

Reaction notes

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