Hydrochloric Acid → HCID 20398034, compound

HRID 462392Notes

Reaction equation

HRID 462392 reaction equation
C[O:2][C:3](=[O:22])[CH2:4][CH2:5][CH:6]=[C:7]=[CH:8][CH2:9][S:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21].O.[OH-].[Li+].Cl>C(O)C>[C:3]([OH:22])(=[O:2])[CH2:4][CH2:5][CH:6]=[C:7]=[CH:8][CH2:9][S:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 3939Lithium HydroxideHCID 20397918HCID 20397918, compound

Product 1

HCID 20398034HCID 20398034, compoundYield 59.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Methyl-8-thianonadeca-4,5-dienoate (210 mg) was treated in 10 ml of ethanol and 1 ml of water with 160 mg of lithium hydroxide at room temperature for 18 hours. The solution was acidified to pH 4 with dilute HCl and extracted with diethyl ether twice. The ethereal extracts were washed with brine and dried over potassium carbonate to give 120 mg of 8-thianonadeca-4,5-dienoic acid. This procedure can be used to convert the compounds of Example VI to their corresponding acid.

Workup

  1. extractionextracted with diethyl ether twice
  2. washThe ethereal extracts were washed with brine
  3. dry with materialdried over potassium carbonate

Sources & evidence

ORD record
ord-671f7947c6a8469d886ab0ab0a9f6fc3
Source dataset
uspto-grants-1985_05
Patent number
US04515727

Reaction notes

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