Hydrochloric Acid → HCID 70489857, compound

HRID 462434Notes

Reaction equation

HRID 462434 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:9][C:8]([CH2:10][S:11][CH2:12][CH2:13][NH:14][C:15]([NH:20][CH2:21][CH2:22][OH:23])=[CH:16][N+:17]([O-:19])=[O:18])=[CH:7][CH:6]=1)[CH3:3].C(O)(C)C.[ClH:28]>C(O)C>[ClH:28].[CH3:3][N:2]([CH2:4][C:5]1[O:9][C:8]([CH2:10][S:11][CH2:12][CH2:13][NH:14][C:15]([NH:20][CH2:21][CH2:22][OH:23])=[CH:16][N+:17]([O-:19])=[O:18])=[CH:7][CH:6]=1)[CH3:1]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3776IsopropanolHCID 70489858HCID 70489858, compound

Product 1

HCID 70489857HCID 70489857, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

a 20 g sample of N-[2-[[(5-[(dimethylamino)methyl]-2-furanyl)methyl]thio]ethyl]-N'-(2-hydroxyethyl)-2-nitro-1,1-ethenediamine (58 mmoles) was dissolved in 100 ml of ethanol (99-100%) and there were added slowly 25 ml of isopropyl alcohol containing 58 mmoles of hydrochloric acid. The mixture was left under stirring overnight and the solid precipitate was filtered, washed with ethanol and dried to give 18 g of N-[2-[[(5-[(dimethylamino)methyl]-2-furanyl)methyl]thio]ethyl]-N'-(2-hydroxyethyl)-2-nitro-1,1-ethenediamine hydrochloride, in the form of white crystals, soluble in water and methanol, m.p. 119°-122° C.

Workup

  1. waitThe mixture was left
  2. filtrationthe solid precipitate was filtered
  3. washwashed with ethanol
  4. customdried

Sources & evidence

ORD record
ord-f8ad842a36894409942480e49d4e4544
Source dataset
uspto-grants-1985_05
Patent number
US04515806

Reaction notes

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