Nitrogen → N~1~-Ethyl-N~1~-heptylethane-1,2-diamine

HRID 463675Notes

Reaction equation

HRID 463675 reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].N#N.[CH2:9]([N:11]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH2:12][C:13]#[N:14])[CH3:10]>C1COCC1>[CH2:9]([N:11]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH2:12][CH2:13][NH2:14])[CH3:10]

Participants

5

Reactant 3

HCID 947NitrogenHCID 202253242-[Ethyl(heptyl)amino]acetonitrileHCID 21226445Aluminium lithium hydride

Product 1

HCID 13491110N~1~-Ethyl-N~1~-heptylethane-1,2-diamine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Suspend 1.2 g (0.032 moles) lithium aluminum hydride in 20 ml THF. Chill the suspension to -10° C. under a stream of N2. Slowly add 7.90 g (0.043 moles) 2-[ethyl(heptyl)amino]acetonitrile to the suspension. Stir for 2 hrs at ambient temperature. Quench the reaction mixture with Na2SO4 ·10H2O and H2O. Filter the quenched reaction mixture and evaporate the solvents to provide the title compound. (B.P.: 42°-45° C./0.015 mmHg).

Workup

  1. customQuench the reaction mixture with Na2SO4 ·10H2O and H2O
  2. filtrationFilter
  3. customthe quenched reaction mixture
  4. customevaporate the solvents

Sources & evidence

ORD record
ord-fa9627ca3221447e902ead32fff836e0
Source dataset
uspto-grants-1985_10
Patent number
US04544654

Reaction notes

Loading…