Methyl iodide → HCID 20265013, compound

HRID 463690Notes

Reaction equation

HRID 463690 reaction equation
[N+:1]([C:4]1[C:17]2[C:16](=[O:18])[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[NH:9][C:8]=2[CH:7]=[CH:6][CH:5]=1)([O-:3])=[O:2].[H-].[Na+].[CH3:21]I>CN(C)C=O>[CH3:21][N:9]1[C:10]2[C:15](=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:16](=[O:18])[C:17]2[C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=[CH:7][C:8]1=2

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 24758Sodium hydrideHCID 988489(10H)-Acridinone, 1-nitro-

Product 1

HCID 20265013HCID 20265013, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

4.8 g of 1-nitro-9-acridanone are dissolved in 200 ml of dimethylformamide and treated with 0.5 g of sodium hydride. The deep red solution is treated with 2.5 ml of methyl iodide and stirred at room temperature for 4 hours. The yellow precipitate obtained is filtered and washed successively with dimethylformamide, water, ethanol and ether. There is obtained 10-methyl-1-nitro-9-acridanone of melting point 308°-309°.

Workup

  1. customThe yellow precipitate obtained
  2. filtrationis filtered
  3. washwashed successively with dimethylformamide, water, ethanol and ether

Sources & evidence

ORD record
ord-f447da1f560c46aaa2e9b4783110f236
Source dataset
uspto-grants-1985_10
Patent number
US04544659

Reaction notes

Loading…