Benzyl Bromide → HCID 20265079, compound

HRID 463755Notes

Reaction equation

HRID 463755 reaction equation
Cl.[NH2:2][C:3]1[CH:11]=[CH:10][C:6]2[O:7][CH:8]=[CH:9][C:5]=2[CH:4]=1.[CH2:12](Br)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.C([O-])(O)=O.[Na+]>CS(C)=O>[CH2:12]([N:2]([CH2:9][C:5]1[CH:6]=[CH:10][CH:11]=[CH:3][CH:4]=1)[C:3]1[CH:11]=[CH:10][C:6]2[O:7][CH:8]=[CH:9][C:5]=2[CH:4]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 7498Benzyl BromideHCID 516892Sodium BicarbonateHCID 20265066HCID 20265066, compound

Product 1

HCID 20265079HCID 20265079, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

A stirred solution of 5-aminobenzo[b]furan hydrochloride in dry DMSO is treated with excess benzyl bromide followed by solid NaHCO3 to give the title compound.

Sources & evidence

ORD record
ord-624526e4dd7241a7be30770eeb0f29e5
Source dataset
uspto-grants-1985_10
Patent number
US04544667

Reaction notes

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