Sodium Hydroxide → Azobisisobutyronitrile

HRID 464110Notes

Reaction equation

HRID 464110 reaction equation
[OH-].[Na+].[NH2:3][C:4]([CH3:8])([CH3:7])[C:5]#[N:6]>CCCCCCCCCCCCCCCC[N+](C)(C)C.[Cl-]>[N:3]([C:4]([CH3:8])([CH3:7])[C:5]#[N:6])=[N:3][C:4]([CH3:8])([CH3:7])[C:5]#[N:6]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 880222-Amino-2-methylpropionitrile

Product 1

HCID 6547AzobisisobutyronitrileYield 96%

Reagents, catalysts & solvents 1

HCID 8154Hexadecyltrimethylammonium chlorideCatalyst

Conditions

Temperature
20 °C

Procedure

3 ml of `Arquad 16-29` is added, followed by 2.2 equivalents of caustic soda. While maintaining the temperature at 20° C., 26 mg of 2-amino-2-methyl-propanenitrile is added over 20 minutes and the title compound is isolated as in Example 1. Yield 96%.

Sources & evidence

ORD record
ord-2477a7439aed43528a1ce2062e84846d
Source dataset
uspto-grants-1985_10
Patent number
US04546174

Reaction notes

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