Potassium Carbonate → Ethyl 2-(6-chloro-3-nitro-2-pyridinyl)oxypropanoate

HRID 464228Notes

Reaction equation

HRID 464228 reaction equation
[N+:1]([C:4]1[C:5]([OH:11])=[N:6][C:7]([Cl:10])=[CH:8][CH:9]=1)([O-:3])=[O:2].Br[CH:13]([CH3:19])[C:14]([O:16][CH2:17][CH3:18])=[O:15].C(=O)([O-])[O-].[K+].[K+]>CS(C)=O>[Cl:10][C:7]1[N:6]=[C:5]([O:11][CH:13]([CH3:19])[C:14]([O:16][CH2:17][CH3:18])=[O:15])[C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 79040Ethyl 2-bromopropionateHCID 178526634HCID 178526634, compound

Product 1

HCID 13245757Ethyl 2-(6-chloro-3-nitro-2-pyridinyl)oxypropanoate

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

A mixture of 8.8 grams of 3-nitro-6-chloro-2-pyridinol, 9 grams of ethyl α-bromopropionate and 6 grams of potassium carbonate was stirred in 50 ml of DMSO (dimethylsulfoxide) at ambient temperature for approximately 48 hours.

Sources & evidence

ORD record
ord-c371f7fa04f6410a9daf14678034b5f7
Source dataset
uspto-grants-1985_10
Patent number
US04547218

Reaction notes

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