Thiophosgene → HCID 20262974, compound

HRID 464428Notes

Reaction equation

HRID 464428 reaction equation
[ClH:1].Cl[C:3]1[CH:4]=[C:5]([CH:12]=[C:13]([Cl:15])[CH:14]=1)[O:6][CH:7]1[CH2:11][CH2:10][NH:9][CH2:8]1.[C:16](Cl)([Cl:18])=[S:17]>C(N(CC)CC)C>[Cl:15][C:13]1[CH:12]=[C:5]([CH:4]=[CH:3][C:14]=1[Cl:1])[O:6][CH:7]1[CH2:11][CH2:10][N:9]([C:16]([Cl:18])=[S:17])[CH2:8]1

Participants

4

Reactant 2

HCID 10040ThiophosgeneHCID 20263068HCID 20263068, compound

Product 1

HCID 20262974HCID 20262974, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

3-(3,5-Dichlorophenoxy)pyrrolidine hydrochloride in a solvent mixture with excess tri-ethylamine is reacted with thiophosgene to give the title compound. The triethylamine hydrochloride by-product is removed by filtration and the product isolated by evaporating off excess solvent and triethylamine.

Sources & evidence

ORD record
ord-589e96f11b9747efaf6bb1b608ecd5f2
Source dataset
uspto-grants-1985_10
Patent number
US04547514

Reaction notes

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