3-(1-Methylpyrrolidin-2-yl)piperidine → HCID 20261497, compound

HRID 465090Notes

Reaction equation

HRID 465090 reaction equation
Cl[CH2:2][C:3]([N:5]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[C:9](=[O:16])[NH:8][C:7]2[CH:17]=[CH:18][CH:19]=[CH:20][C:6]1=2)=[O:4].[NH:21]1[CH2:26][CH:25]([CH:27]2[CH2:32][CH2:31][CH2:30][N:28]2[CH3:29])[CH2:24][CH2:23][CH2:22]1>C(OCC)(=O)C>[CH3:29][N:28]1[CH2:30][CH2:31][CH2:32][CH:27]1[CH:25]1[CH2:24][CH2:23][CH2:22][N:21]([CH2:2][C:3]([N:5]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[C:9](=[O:16])[NH:8][C:7]3[CH:17]=[CH:18][CH:19]=[CH:20][C:6]2=3)=[O:4])[CH2:26]1

Participants

4

Reactant 2

HCID 2194583-(1-Methylpyrrolidin-2-yl)piperidineHCID 100854195-(chloroacetyl)-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one

Product 1

HCID 20261497HCID 20261497, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound is prepared analogously to Example 35 from 5-(chloroacetyl)-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one and hexahydronicotine to give colorless crystals, mp. 161°-163° C. (ethyl acetate).

Sources & evidence

ORD record
ord-0bbdb77a847b48aebe2fd3b6a764db7c
Source dataset
uspto-grants-1985_10
Patent number
US04550107

Reaction notes

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