Hydrochloric Acid → 2-Hydrazinoimidazoline dihydrochloride

HRID 465092Notes

Reaction equation

HRID 465092 reaction equation
Br.[NH:2]([C:4]1[NH:5][CH2:6][CH2:7][N:8]=1)[NH2:3].[ClH:9]>C(O)C.C(O)(C)C>[ClH:9].[ClH:9].[NH:2]([C:4]1[NH:8][CH2:7][CH2:6][N:5]=1)[NH2:3]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 30850992-Hydrazino-delta-2-imidazoline hydrobromide

Product 1

HCID 122212312-Hydrazinoimidazoline dihydrochloride

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 3776IsopropanolSolvent

Procedure

A 50 g portion of 2-hydrazino-2-imidazoline hydrobromide was dissolved in 750 ml of hot absolute ethanol and treated with 100 ml of 6N hydrochloric acid in isopropanol. The precipitate was collected, washed with ethanol, dried, dissolved in 2300 ml of hot absolute ethanol, filtered and the filtrate treated with 6N hydrochloric acid in isopropanol, then cooled, giving 37 g of the desired intermediate, mp 185°-187° C.

Workup

  1. customThe precipitate was collected
  2. washwashed with ethanol
  3. customdried
  4. dissolutiondissolved in 2300 ml of hot absolute ethanol
  5. filtrationfiltered
  6. additionthe filtrate treated with 6N hydrochloric acid in isopropanol
  7. temperaturecooled

Sources & evidence

ORD record
ord-1e95a948e50140318012a256adde7ecd
Source dataset
uspto-grants-1985_10
Patent number
US04550169

Reaction notes

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