Hydrochloric Acid → HCID 178459181, compound

HRID 46568Notes

Reaction equation

HRID 46568 reaction equation
[F:1][C:2]1[CH:17]=[CH:16][C:5]([C:6]([C:8](=[C:11]([O:14]C)[CH2:12][CH3:13])[C:9]#[N:10])=[O:7])=[CH:4][CH:3]=1.Cl>C(Cl)(Cl)Cl>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([C:8](=[C:11]([OH:14])[CH2:12][CH3:13])[C:9]#[N:10])=[O:7])=[CH:16][CH:17]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 538000562-(p-Fluorobenzoyl)-3-methoxy-2-pentenonitrile

Product 1

HCID 178459181HCID 178459181, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A two-phase mixture of 5.0 g. 2-(p-fluorobenzoyl)-3-methoxy-2-pentenonitrile in 50 ml. of chloroform is stirred with a 50 ml. solution of aqueous 1 N hydrochloric acid. After 24 hours, the organic phase is separated and evaporated. The residue is recrystallized from chloroform to yield the title compound.

Workup

  1. additionA two-phase mixture of 5.0 g
  2. customthe organic phase is separated
  3. customevaporated
  4. customThe residue is recrystallized from chloroform

Sources & evidence

ORD record
ord-3fd7ec61b5f6425d86f700f94a3a5316
Source dataset
uspto-grants-1979_11
Patent number
US04173650

Reaction notes

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