Hydrochloric Acid → HCID 15158150, compound

HRID 466030Notes

Reaction equation

HRID 466030 reaction equation
Cl.C[O:3][C:4]1[N:5]=[N:6][CH:7]=[CH:8][C:9]=1[C:10]1[C:11]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[N:12][N:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=12>O>[O:3]=[C:4]1[C:9]([C:10]2[C:11]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[N:12][N:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=23)=[CH:8][CH:7]=[N:6][NH:5]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15158146HCID 15158146, compound

Product 1

HCID 15158150HCID 15158150, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A concentrated hydrochloric acid (5 ml) was added to 3-(3-methoxypyridazin-4-yl)-2-phenylpyrazolo[1,5-a]pyridine (0.50 g) and refluxed for 2 hours and 30 minutes. After cooling, to the reaction mixture was added water (10 ml). The precipitates were collected by filtration to give 3-(3-oxo-2,3-dihydropyridazin-4-yl)-2-phenylpyrazolo[1,5-a]pyridine (0.41 g).

Workup

  1. temperaturerefluxed for 2 hours and 30 minutes
  2. temperatureAfter cooling, to the reaction mixture
  3. filtrationThe precipitates were collected by filtration

Sources & evidence

ORD record
ord-4a35cc6bc94d47d68a810cd389e69dc0
Source dataset
uspto-grants-1992_10
Patent number
US05155114

Reaction notes

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