反应详情

温度

220 °C

4-Phenoxyphenyl propargyl ether (33.7 g, 150 mmol) in 50 mL of N,N-diethylaniline is added to refluxing (220° C.) N,N-diethylanile (300 ml) dropwise over a period of 10 minutes under nitrogen. The mixture is stirred at reflux for 8 hours, cooled and evaporated under high vacuum (bath temp. ~80° C.) to remove solvents. The residue is distilled to give 6-phenoxy-2H-1-benzopyran; b.p. 147°-150° C./0.5 mmHg.

1. temperatureat reflux for 8 hours
2. temperaturecooled
3. customevaporated under high vacuum (bath temp. ~80° C.)
4. customto remove solvents
5. distillationThe residue is distilled