Anthranilic Acid → HCID 19813270, compound

HRID 466985Notes

Reaction equation

HRID 466985 reaction equation
[S:1]1[CH:5]=[CH:4][S:3][C:2]1=[C:6]([C:13]([O:15]C(OCC)=O)=O)[C:7]([O:9][CH:10]([CH3:12])[CH3:11])=[O:8].[C:21]([OH:30])(=[O:29])[C:22]1[C:23](=[CH:25][CH:26]=[CH:27][CH:28]=1)[NH2:24]>CN(C=O)C>[S:3]1[CH:4]=[CH:5][S:1][C:2]1=[C:6]([C:13](=[O:15])[NH:24][C:23]1[CH:25]=[CH:26][CH:27]=[CH:28][C:22]=1[C:21]([OH:30])=[O:29])[C:7]([O:9][CH:10]([CH3:11])[CH3:12])=[O:8]

Participants

4

Reactant 2

HCID 227Anthranilic AcidHCID 19813261HCID 19813261, compound

Product 1

HCID 19813270HCID 19813270, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
60 °C

Procedure

Isopropyl 2-(1,3-dithiol-2-ylidene)-2-(ethoxycarbonyloxy-carbonyl)acetate (15.9 g) and anthranilic acid (14 dissolved in DMF (100 ml). The mixture was stirred at 60° C. for hrs. The reaction mixture was poured into ice-water. The solid formed was filtered and recrystallized from ethyl acetate to give the titled compound. (5.6 g, 30.7%)

Workup

  1. customThe solid formed
  2. filtrationwas filtered
  3. customrecrystallized from ethyl acetate

Sources & evidence

ORD record
ord-152f9c6579cd44b89a96116681b901a5
Source dataset
uspto-grants-1992_10
Patent number
US05158950

Reaction notes

Loading…