反应详情

A stirred mixture of 1-benzoyl-4-methylthiosemicarbazide (20.9 g, 1.00×10-1 mole) and 1 molar aqueous NaHCO3 (1000 ml, 1 mole) was heated to reflux. After refluxing overnight the reaction was cooled in an ice bath. With stirring the solution was carefully acidified by the dropwise addition of conc. HCl (92 ml, 1.1 mole). A colorless precipitate formed and this was subsequently collected by filtration.

1. temperaturewas heated to reflux
2. temperatureAfter refluxing overnight the reaction
3. temperaturewas cooled in an ice bath
4. customA colorless precipitate formed
5. filtrationthis was subsequently collected by filtration