HRID467329

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(CN1C(=O)c2ccccc2C1=O)C(C)(C)C(C)(OP(=O)(O)O)P(=O)(O)O

HCID86744990

未命名化合物

PRODUCTS

生成物

HCID2088

Alendronic Acid

C4H13NO7P2

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID313

Hydrochloric Acid

ClH

PROCEDURE

实验过程

Tetramethyl-1,1-bisphosphono-1-hydroxy-4-phthalimidobutane 40 g (0.091 mole) from Step 4 was dissolved in 200 ml of 6N HCl and the solution refluxed for 18 hours.

WORKUP

后处理

temperaturethe solution refluxed for 18 hours