反应详情

A solution of 8 g of N-phenethyl-3,4-dimethoxyphenethylamine, 8 g of anhydrous potassium carbonate, 11 ml of propyl iodide and 80 ml of acetone was refluxed for 6 hours and the mixture was filtered. The filtrate was evaporated to dryness and the residue was taken up in 50 ml of water. The solution was extracted with methylene chloride and the organic extracts were washed with water, dried over magnesium sulfate, filtered and evaporated to dryness to obtain 9.37 g of raw N-phenethyl-N-propyl-3,4-dimethoxyphenethylamine in the form of an oil which was used as is for the next step.

1. filtrationthe mixture was filtered
2. customThe filtrate was evaporated to dryness
3. extractionThe solution was extracted with methylene chloride
4. washthe organic extracts were washed with water
5. dry with materialdried over magnesium sulfate
6. filtrationfiltered
7. customevaporated to dryness