反应详情

3.8 g of N-[4-methoxy-3-(trifluoromethyl)benzyl]formamide was dissolved in 20 ml ethanol, 2 ml conc. hydrochloric acid was added thereto, and the mixture was heated under reflux for 3 hr. After cooling, diethyl ether was added thereto, and the resulting crystals were collected by filtration to give 2.5 g of 4-methoxy-3-(trifluoromethyl)benzylamine hydrochloride.

1. temperaturethe mixture was heated
2. temperatureunder reflux for 3 hr
3. temperatureAfter cooling
4. filtrationthe resulting crystals were collected by filtration